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Updated: Jun 11, 2025

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High-throughput Antiviral Assays to Screen for Inhibitors of Zika Virus Replication
Published on: October 30, 2021
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Identification and detection of conserved G-quadruplex in monkeypox virus using conformation specific fluorogenic
Sumon Pratihar1, Ramjayakumar Venkatesh1, Mohamed Nabeel Mattath1
1Bioorganic Chemistry Laboratory, New Chemistry Unit, Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), Jakkur, P.O., Bengaluru, 560064 Karnataka, India. tgraju@jncasr.ac.in.
Abstract:
Identifying distinct noncanonical structures in pathogenic genomes is crucial for developing new diagnostic tools. This study uncovers stable G-quadruplex (GQ) structures in conserved DNA sequences unique to the monkeypox virus (MPV). Furthermore, we developed a method for the detection of target GQ using a fluorogenic probe.

