Genetic-Dependent Brain Signatures of Resilience: Interactions among Childhood Abuse, Genetic Risks and Brain

Han Lu1,2, Edmund T Rolls3, Hanjia Liu1

  • 1National Clinical Research Center for Aging and Medicine at Huashan Hospital, MOE Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai 200433, China.

Summary

Childhood abuse impacts adolescent mental health. A genetic-dependent brain (GDB) signature in girls, involving orbitofrontal networks, predicts resilience to emotional disorders, offering hope for targeted interventions.

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