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Updated: Jun 11, 2025

Total Internal Reflection Absorption Spectroscopy TIRAS for the Detection of Solvated Electrons at a Plasma-liquid Interface
Published on: January 24, 2018
Iron TAMs: The fallen protectors
Lijuan Sun1, Mikala Egeblad1,2
1Department of Cell Biology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Abstract:
A new study by Folkert et al. (https://doi.org/10.1084/jem.20230420) defines an "iron-rich" subset of tumor-associated macrophages (iTAMs). The metabolism of heme leads to the degradation of the transcriptional repressor Bach1 and shapes the transcriptional profile of iTAMs. The endothelin receptor B in iTAMs signals tumor-supportive functions.
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