Improving the Agreement Between the First Heart-Rate-Variability Threshold and the Gas-Exchange Threshold

The first heart-rate (HR) -variability (HRV) -derived threshold based on detrended fluctuation analysis alpha 1 (DFA a1) has shown inconsistent agreement with the gas-exchange threshold (GET). This study examined whether a custom method of computing the first HRV threshold (HRVT1) based on individual HRV characteristics would improve agreement.

Fourteen participants underwent ramp incremental testing measuring gas-exchange variables and RR intervals. Comparisons were made between the oxygen consumption (V˙O2)/HR at the GET versus the V˙O2/HR at the standard DFA a1 = 0.75 (HRVT1s) or a custom value (HRVT1c) based on the DFA a1 midway between the maximum seen during the early ramp incremental and 0.5.

Mean values for GET V˙O2 versus HRVT1s V˙O2 and GETHR versus HRVT1sHR were statistically different (25.4 [3.3] vs 29.8 [6.8] mL·kg-1·min-1, P = .01, d = 0.80; 131 [11] vs 146 [22] beats·min-1, P = .005, d = 0.91). There were no statistical differences when using the HRVT1c (25.4 [3.3] vs 25.1 [5.7] mL·kg-1·min-1, P = .77, d = 0.08; 131 [11] vs 132 [17] beats·min-1, P = .65, d = 0.12). Equivalence between GET and HRVT1c V˙O2/HR was also verified. Mean maximal DFA a1 during the early ramp incremental was 1.52 (0.22) with mean HRVT1c of 1.01 (0.11). Pearson r correlation coefficients were between .67 and .70 for all GET to HRVT1 comparisons. The second HRV threshold and respiratory compensation point parameters showed agreement and correlations in line with prior studies.

The HRVT1c showed stronger agreement to GET parameters than seen using the HRVT1s. It is recommended that evaluations of the HRVT1 consider this approach in determining the HR and V˙O2 at this threshold.