Related Experiment Video
Updated: Jun 11, 2025
05:05
Ultrasound Cyclo Plasty in Eyes with Glaucoma
Published on: January 26, 2018
12.1K
Manometric Intraocular Pressure Reduction with Negative Pressure Using Ocular Pressure Adjusting Pump Goggles.
Katherine S Peters1, Enrico Brambilla2, Tanner Ferguson1
1Vance Thompson Vision, Sioux Falls, South Dakota.
Ophthalmology. Glaucoma
|September 30, 2024
Summary
The ocular pressure adjusting pump uses negative pressure to lower intraocular pressure (IOP) effectively. This noninvasive device demonstrated a dose-dependent IOP reduction in patients undergoing cataract surgery.
Area of Science:
- Ophthalmology
- Medical Devices
- Physiology
Background:
- A novel noninvasive, nonpharmacological device, the ocular pressure adjusting pump, utilizes negative pressure (NP) goggles to reduce intraocular pressure (IOP).
- Understanding the physiological effects of NP on IOP is crucial for developing new glaucoma treatment strategies.
Purpose of the Study:
- To evaluate the efficacy of the ocular pressure adjusting pump in lowering IOP using continuous direct manometry.
- To determine the dose-dependent relationship between negative pressure levels and IOP reduction.
Main Methods:
- A prospective, single-arm, single-center physiological study.
- Adult patients undergoing cataract surgery were enrolled.
- Direct manometry via an anterior chamber cannula measured IOP continuously at baseline, -10 mmHg NP, and -20 mmHg NP.
Main Results:
- A dose-dependent reduction in IOP was observed in all 17 subjects.
- Mean IOP decreased by 33% with -10 mmHg NP and 51% with -20 mmHg NP.
- IOP returned to baseline upon discontinuation of NP, with no instances of IOP increase.
Conclusions:
- The ocular pressure adjusting pump effectively reduces IOP in a dose-dependent manner.
- The IOP-lowering effect is reversible, with IOP returning to baseline after NP cessation.
- This device presents a promising nonpharmacological approach for IOP management.
Related Concept Videos
01:27Open Angle Glaucoma: Treatment
403
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
403
01:25Glaucoma: Overview
527
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
527
01:28Angle Closure Glaucoma: Treatment
448
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
448