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Updated: Jul 11, 2026

Obtaining High Quality RNA from Single Cell Populations in Human Postmortem Brain Tissue
Published on: August 6, 2009
Profiling expressing features of surface proteins on single-exosome in first-episode Schizophrenia patients: a
Sijie Zhang1, Aijun Liao1, Yujue Wang1
1Department of Psychiatry, National Clinical Research Center for Mental Disorders, and National Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China.
Abstract:
Proximity barcoding assay, a high-throughput method for single-exosome analysis, was employed to profile surface proteins on individual exosomes of SCZ patients. This analysis identified five differentially expressed proteins (DEPs) between SCZ patients and healthy controls (HC) and six DEPs between antipsychotic responders and non-responders. Furthermore, two exosome clusters were found to be associated with SCZ, and certain DEPs were correlated with cognitive functions.
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