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Buruli ulcer: An epidemiological update from Japan
Ryo Fukaura1, Manabu Ato2, Chiaki Murase1
1Department of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
The Journal of Dermatology
|October 1, 2024
Summary
Buruli ulcer (BU) cases in Japan, caused by Mycobacterium ulcerans subsp. shinshuense, are increasing. Despite good healthcare, delayed diagnosis is common due to low awareness among professionals.
Area of Science:
- Microbiology
- Infectious Diseases
- Public Health
Background:
- Buruli ulcer (BU) is a neglected tropical disease caused by Mycobacterium ulcerans.
- Japan, a non-tropical country, has documented cases of BU, with Mycobacterium ulcerans subsp. shinshuense identified as the causative agent.
- The first report of BU in Japan was in 1982, with a recent increase in cases.
Purpose of the Study:
- To provide an updated overview of Buruli ulcer cases in Japan.
- To raise awareness of BU among dermatologists and healthcare professionals in non-endemic settings.
Main Methods:
- Review of documented Buruli ulcer cases in Japan.
- Analysis of case distribution and trends over time.
- Discussion of diagnostic challenges and healthcare system's role.
Main Results:
- A total of 87 Buruli ulcer cases have been reported in Japan to date.
- A significant increase in cases is observed, with 50 cases (57.7%) reported in the last decade.
- Japan's advanced healthcare facilitates favorable prognoses but delayed diagnoses occur due to low awareness.
Conclusions:
- Buruli ulcer incidence is rising in Japan, necessitating increased vigilance.
- Healthcare professionals require enhanced education on BU recognition and diagnosis in non-endemic areas.
- Prompt diagnosis and treatment are crucial for managing Buruli ulcer effectively.
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