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Multiple Pipe Systems

Multiple Pipe Systems

Multipipe systems consist of complex configurations of interconnected pipes designed to transport fluids efficiently across intricate networks. They are essential in engineering applications requiring precise control over flow distribution, pressure, and head loss. They are categorized into series, parallel, loop, and network configurations, each distinguished by unique flow characteristics and applications.
Series Configuration
In a series configuration, fluid flows sequentially from one pipe...

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Updated: Jun 11, 2025

Cell Co-culture Patterning Using Aqueous Two-phase Systems

Cell Co-culture Patterning Using Aqueous Two-phase Systems

Published on: March 26, 2013

Aqueous two-phase systems - versatile and advanced (bio)process engineering tools.

Alexandre M S Jorge¹, Jorge F B Pereira¹

¹University of Coimbra, CERES, FCTUC, Department of Chemical Engineering, Rua Sílvio Lima, Pólo II - Pinhal de Marrocos, 3030-790 Coimbra, Portugal. jfbpereira@eq.uc.pt.

Chemical Communications (Cambridge, England)

|October 1, 2024

Summary

This summary is machine-generated.

Aqueous two-phase systems (ATPS) offer versatile platforms for separating biomolecules and valuable compounds. These systems are expanding into health, biomedicine, and material sciences, showing great potential for innovation.

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Area of Science:

Biotechnology
Biochemistry
Chemical Engineering

Background:

Aqueous two-phase systems (ATPS) are liquid-liquid extraction systems used since the 1950s.
ATPS are biocompatible, flexible, and versatile, addressing challenges in conventional separation methods.
Applications have expanded from biotechnology to health, biomedicine, and material sciences.

Purpose of the Study:

To discuss the fundamentals and molecular mechanisms of ATPS.
To explore innovative applications of ATPS in downstream processing.
To provide insights into integrated upstream-downstream platforms and their use as pre-treatment and analytical tools.

Main Methods:

Review of fundamental principles of ATPS formation and molecular mechanisms.
Exploration of prominent and innovative applications in downstream processing.
Discussion of integrated platforms, pre-treatment, and analytical applications.

Main Results:

ATPS demonstrate significant potential in various scientific fields.
New applications include all-aqueous emulsions, microfluidic systems, and membrane-free batteries.
Advancements are presented in bioengineering and biotechnology.

Conclusions:

ATPS possess transformative potential across diverse scientific disciplines.
Future research should focus on maximizing ATPS capabilities and overcoming existing challenges.
ATPS are poised to drive innovation in biotechnology and beyond.