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Related Experiment Video

Updated: Jun 11, 2025

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Biodesign: Engineering an aortic endograft explantation tool.

Solyman Hatami1, Vamsi Maturi1, Alwin Mathew1

  • 1Texas A&M School of Engineering Medicine, Houston, TX.

Journal of Vascular Surgery Cases and Innovative Techniques
|October 1, 2024
PubMed
Summary

Graft explantation after endovascular aortic repair (EVAR) is risky. A novel device was developed to safely remove EVAR grafts, reducing complications and improving patient outcomes.

Keywords:
Abdominal aortic aneurysmAortic graft infectionBiomedical innovationEVAR explantationOpen endograft explantation

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Area of Science:

  • Biomedical Engineering
  • Vascular Surgery
  • Medical Device Design

Background:

  • Endovascular aortic repair (EVAR) graft failure occurs in 16-30% of cases, often requiring explantation.
  • Graft explantation carries significant risks, including endothelial damage (31% morbidity, 6.3% mortality).
  • Current explantation methods are suboptimal, lacking dedicated devices.

Purpose of the Study:

  • To design and prototype a novel device for safe and effective explantation of EVAR endografts.
  • To address the limitations of current explantation techniques and reduce associated complications.

Main Methods:

  • Utilized the biodesign process to develop multiple explantation device prototypes.
  • Simulated grafted aortas using silicone tubing and tested prototypes against design criteria.
  • Iteratively improved the most promising prototype based on surgeon feedback.

Main Results:

  • The most effective prototype features a tapered lumenal geometry and stainless steel beads to minimize aortic damage.
  • The device demonstrated ease of use with a distal grip and latching mechanism for controlled removal.
  • Prototyping confirmed the device's feasibility and effectiveness in safe EVAR explantation.

Conclusions:

  • A novel device has been developed for safe EVAR endograft explantation.
  • This device has the potential to significantly reduce morbidity and mortality associated with EVAR explantation.
  • Further clinical evaluation is warranted to confirm the device's efficacy in practice.