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Updated: Jun 11, 2025

Author Spotlight: Enhancing Success of Ultrasound-Guided Neuraxial Anesthesia in Cases with Difficult Anatomy
Published on: January 31, 2025
A successful combined spinal-epidural anesthesia for cesarean section in a patient with neurofibromatosis type
Hitomi Taka1, Nobuyoshi Kusama2, Minami Sakamoto2
1Department of Anesthesiology and Intensive Care Medicine, Nagoya City University West Medical Center, 1-1-1, Hirate-Cho, Kita-Ku, Nagoya, Aichi, 462-8508, Japan. h.taka0311@gmail.com.
Background:
Dural ectasia is a common manifestation of neurofibromatosis type 1. Although there have been reports of unsuccessful spinal anesthesia due to dual ectasia in Marfan syndrome, reports describing similar unsuccessful spinal anesthesia in neurofibromatosis type 1 are lacking.
Case Presentation:
A parturient with neurofibromatosis type 1 was scheduled for a repeat cesarean section. During a previous cesarean section, she had experienced a failed spinal anesthesia, which resulted in a conversion to general anesthesia. Preoperative lumbar magnetic resonance imaging revealed dural ectasia, which was speculated to be the cause of the previous spinal anesthesia failure. Therefore, combined spinal-epidural anesthesia was implemented. Because the block level of spinal anesthesia was insufficient as predicted, supplemental administration of epidural anesthesia successfully provided adequate analgesia for the surgery.
Conclusions:
Combined spinal-epidural anesthesia can be useful for the management of cesarean sections in patients with neurofibromatosis type 1-associated dural ectasia.
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