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Updated: Jun 11, 2025

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
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Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics

Published on: March 15, 2024

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Serum apolipoprotein H determines ferroptosis resistance by modulating cellular lipid composition

Xiang He1, Jiahui Zhang1, Masha Huang1

  • 1Department of Biochemistry and Molecular Cell Biology, Shanghai Key Laboratory for Tumor Microenvironment and Inflammation, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Cell Death & Disease
|October 1, 2024
PubMed
Summary

Serum protein apolipoprotein H (APOH) inhibits ferroptosis, a cell death process. APOH activates a pathway that increases fatty acids, preventing ferroptosis and offering potential cancer therapies.

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