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Updated: Jun 11, 2025

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
[Antibiotic antimicrobial stewardship rounds is an effective tool in geriatric clinics]
Emilia Titelman1, Annika Hahlin2
1PhD, överläkare, läkarchef, infektionskliniken, Södersjukhuset; Strama Stockholm.
Abstract:
The antibiotic stewardship round (ASR) is a way to use the knowledge of the infectious disease (ID) specialist to audit and assess the treatment with antibiotics and promote rational use. We implemented ASRs twice a week in two geriatric hospitals and weekly in advanced home care facilities during 9 weeks. All patients treated with antibiotics were discussed and advice regarding the antibiotic treatment was given. In 25 percent of the cases the ID specialist found that the ASR made a difference to the treatment plan, and in 10,8 percent of cases the antibiotic treatment could be discontinued. Other common advice was to switch from intravenous to oral administration and shorten the number of treatment days. Thus, ASRs were found to be an intervention associated with lower and more rational antibiotic use and should be considered an important tool for antimicrobial stewardship in geriatric hospitals.
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