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Updated: Jun 11, 2025

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Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
Published on: May 17, 2024
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[Autologous Breast Reconstruction and Radiotherapy: Consensus Report of the German-Speaking Society for
Albrecht Heine-Geldern1, Christoph Hirche1, Thomas Kremer2
1Klinik für Plastische Chirurgie, Hand- und Rekonstruktive Mikrochirurgie, Handtrauma- und Replantationszentrum, BG Unfallklinik Frankfurt am Main, Frankfurt am Main, Germany.
Summary
Autologous breast reconstruction offers superior outcomes. Postmastectomy radiotherapy (PMRT) is no longer a contraindication for immediate autologous reconstruction, allowing for better symmetry and patient satisfaction.
Area of Science:
- Plastic Surgery
- Oncology
- Microsurgery
Background:
- Autologous postmastectomy breast reconstruction yields favorable long-term clinical and patient-reported outcomes compared to implant-based methods.
- Adjuvant postmastectomy radiotherapy (PMRT) has historically been a contraindication for immediate flap-based reconstruction due to concerns about unpredictable outcomes.
- Modern PMRT techniques have reduced radiation-induced complications, yet surgeons remain hesitant to offer immediate autologous reconstruction to patients requiring radiotherapy.
Purpose of the Study:
- To discuss current literature on PMRT and autologous breast reconstruction.
- To establish consensus among plastic surgeons regarding the safety and efficacy of immediate autologous reconstruction despite subsequent radiotherapy.
- To re-evaluate the role of PMRT as a contraindication for immediate autologous breast reconstruction.
Main Methods:
- A workshop held at the 44th Annual Meeting of the German-speaking Society for Reconstructive Microsurgery (GSRM) in Bern, Switzerland.
- Discussion and review of existing literature concerning PMRT and autologous breast reconstruction.
- Consensus-building among participating plastic surgeons.
Main Results:
- Agreement on the primary goals of postmastectomy reconstruction: creating a soft, sensitive, and symmetrical breast using the safest possible procedure.
- Emphasis on preserving native breast skin envelope through skin- and nipple-sparing techniques.
- Identification of key areas of consensus regarding reconstruction techniques and patient selection.
Conclusions:
- Postmastectomy radiotherapy (PMRT) should no longer be considered a contraindication to immediate autologous breast reconstruction.
- Immediate autologous reconstruction can be safely offered to patients even when adjuvant radiotherapy is anticipated.
- This paradigm shift supports improved aesthetic and functional outcomes for breast cancer survivors undergoing reconstruction.

