Related Experiment Video
Updated: Jun 11, 2025

Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates
Published on: July 6, 2013
[ENT manifestations of congenital cytomegalovirus infection]
Silvia Lambiel1,2,3, Arnaud GréGoire L'huillier4, Angélica Pérez Fornos1
1Service d'ORL et de chirurgie cervicofaciale, Département des neurosciences cliniques, Hôpitaux universitaires de Genève, 1211 Genève 14.
Insights
Cytomegalovirus (CMV) is a common congenital infection. Early diagnosis and antiviral treatment are crucial for infants with CMV to prevent sensorineural hearing loss and vestibular dysfunction.
Area of Science:
- Pediatrics
- Infectious Diseases
- Otolaryngology
Abstract:
Cytomegalovirus is the most common cause of congenital infection worldwide. 90 % of children infected in utero are born without symptoms, but 15 % of them will develop disorders within the first five years of life. The most common disorders affect the inner ear, resulting in sensorineural hearing loss and/or vestibular dysfunction (VD). VD is often unrecognized and confused with conditions -affecting the central nervous system. It can cause delays in psychomotor development and predispose to overall developmental delay. Early diagnosis and treatment are essential to prevent or limit these sequelae. Antiviral treatment during the pre- and neonatal periods should be considered.
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