Case Report: Extramedullary Hematopoiesis in the Prostate

Area of Science:

• Urology
• Hematology
• Pathology

Background:

• Extramedullary hematopoiesis (EMH) is the formation of blood cells outside the bone marrow.
• EMH typically occurs in the spleen, liver, and lymph nodes.
• Prostate EMH is exceptionally rare, with only one prior report in English literature.

Purpose of the Study:

• To report a second case of extramedullary hematopoiesis in the prostate.
• To describe the clinical and pathological findings of prostate EMH.

Main Methods:

• Case presentation of a 56-year-old male patient.
• Digital rectal examination and ultrasound findings.
• Prostate core biopsy for histopathological confirmation.

Main Results:

• A palpable nodule was detected during digital rectal examination.
• Ultrasound revealed distinct findings suggestive of the nodule.
• Histopathology confirmed extramedullary hematopoiesis within the prostate core.

Conclusions:

• Extramedullary hematopoiesis can occur in the prostate, though extremely rare.
• This case adds to the limited documented evidence of prostate EMH.
• Recognition of prostate EMH is important for accurate diagnosis and to avoid misinterpretation.