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Related Concept Videos

One-Way ANOVA: Equal Sample Sizes01:15

One-Way ANOVA: Equal Sample Sizes

One-Way ANOVA can be performed on three or more samples with equal or unequal sample sizes. When one-way ANOVA is performed on two datasets with samples of equal sizes, it can be easily observed that the computed F statistic is highly sensitive to the sample mean.
Different sample means can result in different values for the variance estimate: variance between samples. This is because the variance between samples is calculated as the product of the sample size and the variance between the...
Multiple Comparison Tests01:13

Multiple Comparison Tests

Multiple comparison test, abbreviated as MCT, is a post hoc analysis generally performed after comparing multiple samples with one or more tests. An MCT will help identify a significantly different sample among multiple samples or a factor among multiple factors.
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Randomized Experiments01:13

Randomized Experiments

The randomization process involves assigning study participants randomly to experimental or control groups based on their probability of being equally assigned. Randomization is meant to eliminate selection bias and balance known and unknown confounding factors so that the control group is similar to the treatment group as much as possible. A computer program and a random number generator can be used to assign participants to groups in a way that minimizes bias.
Simple randomization
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Structural Classification of Joints01:20

Structural Classification of Joints

Joints, also known as articulations, are classified based on their structural characteristics, i.e., based on whether the articulating surfaces of the adjacent bones are directly connected by fibrous connective tissue or cartilage, or whether the articulating surfaces contact each other within a fluid-filled joint cavity. These differences serve to divide the joints of the body into three structural classifications.
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Bioequivalence Experimental Study Designs: Completely Randomized and Randomized Block Designs01:20

Bioequivalence Experimental Study Designs: Completely Randomized and Randomized Block Designs

Bioequivalence experimental study designs are crucial methodologies used in evaluating and comparing the bioavailability of different drug products. These designs are categorized into various types: completely randomized, randomized block, repeated measures, cross and carry-over, and Latin square designs.Completely randomized designs involve randomly allocating treatments to all subjects participating in the experiment. This allocation is achieved by assigning unique random numbers to subjects...
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Bioequivalence Experimental Study Designs: Repeated Measures, Cross-Over, Carry-Over, and Latin Square Designs

Bioequivalence experimental study designs play a pivotal role in testing the effectiveness of various treatments. Key among these are the repeated measures, cross-over, carry-over, and Latin square designs. In the repeated measures design, each subject receives all treatments, allowing for temporal comparisons. This type of design is useful in reducing variability but requires careful planning to avoid bias.The cross-over design, an economical method, involves sequential administration of...

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An Improved Mechanical Testing Method to Assess Bone-implant Anchorage
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Full-arch prostheses supported by implants with different macrostructures: A multicenter randomized controlled trial.

Ana Carolina Monachini Marcantonio1, Guilherme José Pimentel Lopes de Oliveira2, Paulo Afonso Tassi3

  • 1Department of Diagnosis and Surgery, School of Dentistry at Araraquara, Univ. Est. Paulista/UNESP, Araraquara, Brazil.

Clinical Implant Dentistry and Related Research
|October 3, 2024
PubMed
Summary
This summary is machine-generated.

Dental implant macrostructure did not impact clinical performance or survival rates in immediate loading of full-arch mandibular prostheses. Both cylindrical with perforating triangular threads (CT) and cylindrical-tapered with combined threads (TST) implants demonstrated predictable outcomes.

Keywords:
implant designimplant‐supported rehabilitationosseointegrationtotal edentulism

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Area of Science:

  • Dental Implantology
  • Biomaterials Science
  • Prosthodontics

Background:

  • Dental implants with hydrophilic surfaces are crucial for osseointegration.
  • Implant macrostructure design influences primary stability and long-term clinical outcomes.
  • Evaluating different macrostructures is essential for optimizing immediate loading protocols.

Purpose of the Study:

  • To compare the clinical performance of two hydrophilic dental implant macrostructures: cylindrical with perforating triangular threads (CT) and cylindrical-tapered with combined threads (TST).
  • To assess survival rates, primary and secondary stability, marginal bone level changes, and peri-implant clinical parameters.
  • To determine the suitability of both implant types for immediate loading of full-arch mandibular prostheses.

Main Methods:

  • A multicenter, split-mouth, simple-blinded, randomized controlled trial.
  • Thirty patients received both CT and TST implants in the edentulous mandible.
  • Primary stability measured by insertion torque and resonance frequency analysis (RFA); clinical parameters and RFA assessed over 24 months; marginal bone level changes evaluated radiographically.

Main Results:

  • Twenty-eight patients completed the 2-year follow-up.
  • Survival rates were 99.16% for CT and 100% for TST implants.
  • No significant differences were observed between CT and TST implants in marginal bone level changes or other clinical parameters.

Conclusions:

  • Implant macrostructure (CT vs. TST) did not influence survival rate, stability, marginal bone loss, or peri-implant health.
  • Both implant designs are suitable for immediate loading of full-arch mandibular prostheses.
  • The findings support the predictable use of these hydrophilic implants regardless of the evaluated macrostructure.