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Updated: Jun 11, 2025

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Cancer Genomes Sometimes Take the Longest Evolutionary Road

Alison M Taylor1

  • 1Department of Pathology and Cell Biology, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, New York.

Cancer Discovery
|October 4, 2024
PubMed
Summary

Researchers developed a new algorithm, Gain Route Identification and Timing In Cancer (GRITIC), to study tumor evolution. GRITIC reveals that genome doubling in tumors often follows indirect paths and affects chromosomal instability.

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