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Related Concept Videos

Gastrulation01:56

Gastrulation

56.8K
Gastrulation establishes the three primary tissues of an embryo: the ectoderm, mesoderm, and endoderm. This developmental process relies on a series of intricate cellular movements, which in humans transforms a flat, “bilaminar disc” composed of two cell sheets into a three-tiered structure. In the resulting embryo, the endoderm serves as the bottom layer, and stacked directly above it is the intermediate mesoderm, and then the uppermost ectoderm. Respectively, these tissue strata...
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Cleavage and Blastulation01:33

Cleavage and Blastulation

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After a large-single-celled zygote is produced via fertilization, the process of cleavage occurs while zygotes travel through the uterine tube. Cleavage is a mitotic cell division that does not result in growth. With each round of successive cell division, daughter cells get increasingly smaller.
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Related Experiment Video

Updated: Jun 11, 2025

Optimized Ex-ovo Culturing of Chick Embryos to Advanced Stages of Development
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Optimized Ex-ovo Culturing of Chick Embryos to Advanced Stages of Development

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Embryonic development grand challenge: crosslinking advances.

Beate Brand-Saberi1

  • 1Department of Anatomy and Molecular Embryology, Institute of Anatomy Universitaetsstrasse, Ruhr University Bochum, Bochum, Germany.

Frontiers in Cell and Developmental Biology
|October 4, 2024
PubMed
Summary
This summary is machine-generated.

Embryonic development research is advancing with new technologies like single-cell transcriptomics and stem cell 3D models. This interdisciplinary field faces challenges with significant implications for biomedical sciences and translational medicine.

Area of Science:

  • Developmental Biology
  • Anatomy
  • Biomedical Sciences
Keywords:
3Rs (reduce replace refine)cell atlas studiesembryoidhigher educationmalformationorganoidoxidative stresstranscriptomics

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  • Translational Medicine

    • Background:

    • Embryonic development research is transitioning to a new era, integrating digitalized collections and advanced techniques.
    • Single-cell level temporo-spatial transcriptomics are increasing attention on embryonic development.
    • The field's complexity spans science, society, and politics, highlighting its interdisciplinary nature and humanitarian implications.