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Association between Behçet's disease and apical periodontitis: A cross-sectional study
Meltem Sümbüllü1, Ayhan Kul2, Ertuğrul Karataş1
1Department of Endodontics, Faculty of Dentistry, Atatürk University, Erzurum, Turkey.
Dental and Medical Problems
|October 4, 2024
Summary
Behçet's disease patients have a significantly higher prevalence of apical periodontitis. Disease severity predicts Behçet's disease, but endodontic treatment success is similar in both groups.
Area of Science:
- Endodontology
- Rheumatology
- Oral Medicine
Background:
- The relationship between Behçet's disease (BD) and apical periodontitis (AP) remains unexplored.
- Investigating this association is crucial for understanding potential systemic links to oral health outcomes.
Purpose of the Study:
- To determine the association between Behçet's disease and apical periodontitis.
- To evaluate the influence of variables such as gender, disease activity, and treatment on this association.
Main Methods:
- A case-control study involving 49 patients with Behçet's disease and 49 controls.
- Radiographic and clinical examinations to diagnose apical periodontitis.
- Statistical analyses including chi-squared tests and logistic regression.
Main Results:
- Apical periodontitis was significantly more prevalent in Behçet's disease patients (OR=5.804, p<0.05).
- BD activity and gender were significantly associated with AP (p<0.05).
- Disease severity emerged as a predictor for Behçet's disease (p<0.05).
Conclusions:
- Patients with Behçet's disease exhibit a markedly higher prevalence of apical periodontitis.
- The success rates of endodontic therapy in BD patients are comparable to those in the general population.

