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Updated: Jun 11, 2025

Isolation and Identification of Extravascular Immune Cells of the Heart
Published on: August 23, 2018
Emerging Biomarkers in Cardiac Sarcoidosis and Other Inflammatory Cardiomyopathies
Joseph El Roumi1, Ziad Taimeh2
1Section of Heart Failure and Transplantation Medicine; Robert and Suzanne Tomsich Department of Cardiovascular Medicine, Miller Family Heart, Vascular & Thoracic Institute; Cleveland Clinic, 9500 Euclid Ave, J3-4, Cleveland, OH, 44195, USA.
Purpose Of Review:
Cardiac sarcoidosis and other inflammatory cardiomyopathies are disorders causing cardiac inflammation and leading to heart failure, arrythmias and cardiac arrest. Diagnosis of these entities remains challenging and multimodal. Thus, there is a growing need to develop reliable biomarkers that can aid in the diagnosis. This review aims to summarize and highlight recent findings in the field of biomarkers for cardiac sarcoidosis and inflammatory cardiomyopathy.
Recent Findings:
Multiple categories of biomarkers including novel molecules are being investigated with the latest evidence showing promising results. Some of these biomarkers are proven to be useful as diagnostic and prognostic aids in cardiac sarcoid and inflammatory cardiomyopathy. The identification of cost-effective and accurate biomarkers is useful not only for enhancing diagnostic accuracy but also for informing therapeutic decision-making processes. This advancement would facilitate the timely institution of immunosuppressive therapies, ultimately leading to improved patient outcomes.
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