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Updated: Jun 11, 2025
04:23
A Swin Transformer-Based Model for Thyroid Nodule Detection in Ultrasound Images
Published on: April 21, 2023
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Radiomics Combined with ACR TI-RADS for Thyroid Nodules: Diagnostic Performance, Unnecessary Biopsy Rate, and
Yan-Jing Zhang1, Tian Xue1, Chang Liu1
1Department of Interventional Ultrasound, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030001, PR China.
Academic Radiology
|October 4, 2024
Summary
A new radiomics nomogram accurately characterizes thyroid nodules, improving diagnostic performance and reducing unnecessary fine needle aspiration biopsy (FNA) rates. This noninvasive method offers a cost-effective approach for thyroid nodule evaluation.
Area of Science:
- Radiology
- Medical Imaging
- Oncology
Background:
- Thyroid nodules are common, requiring accurate characterization to differentiate benign from malignant lesions.
- Current diagnostic methods, such as the American College of Radiology Thyroid Imaging, Reporting and Data System (ACR TI-RADS), have limitations in diagnostic performance.
- Reducing unnecessary fine needle aspiration biopsy (FNA) is crucial for patient management and healthcare costs.
Purpose of the Study:
- To develop and validate a radiomics model for enhanced diagnostic performance in thyroid nodules.
- To reduce the rate of unnecessary fine needle aspiration biopsy (FNA).
- To improve the clinical net benefit of thyroid nodule characterization.
Main Methods:
- A retrospective study of 217 thyroid nodules was conducted, with lesions divided into training and verification cohorts.
- Radiomics scores were derived from B-mode ultrasound (B-US) and strain elastography (SE) images.
- A radiomics nomogram was constructed by combining ultrasonic features and the best-performing radiomics score, and its performance was compared to ACR TI-RADS and a combined advanced clinical score.
Main Results:
- The radiomics nomogram achieved an area under the receiver operating characteristic curve (AUC) of 0.909, significantly higher than the ACR TI-RADS score.
- The nomogram demonstrated an equivalent diagnostic performance to the combined TI-RADS+SE+CEUS score.
- The unnecessary FNA rate was significantly lower with the radiomics nomogram compared to ACR TI-RADS, with comparable rates to the advanced clinical score.
Conclusions:
- The developed radiomics nomogram serves as an objective, accurate, and noninvasive tool for thyroid nodule characterization.
- This approach enhances diagnostic accuracy and reduces unnecessary invasive procedures.
- The radiomics nomogram offers a cost-effective method for improving clinical decision-making in thyroid nodule management.
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