Related Experiment Video
Updated: Jun 11, 2025

07:29
Author Spotlight: Advanced Techniques for Characterizing Tissue Mineralization in Bone Regeneration Research
Published on: September 27, 2024
681
Guided bone regeneration-associated tissue swelling: A digital three-dimensional assessment.
Vrisiis Kofina1, Morvarid Monfaredzadeh2, Swati Y Rawal3
1Assistant Professor and Graduate Periodontics Director, Department of Surgical Sciences, School of Dentistry, Marquette University, Milwaukee, Wisconsin.
The Journal of Prosthetic Dentistry
|October 4, 2024
Summary
Postoperative swelling after guided bone regeneration (GBR) peaked on day 2 and resolved by day 14. Soft tissue thickness and flap advancement influenced bone width outcomes.
Area of Science:
- Dental implantology
- Periodontology
- Oral surgery
Background:
- Postoperative swelling after guided bone regeneration (GBR) can impact interim restorations and treatment timelines.
- Quantitative data on GBR swelling and its effect on regenerative outcomes are currently limited.
Purpose of the Study:
- To quantitatively assess postoperative swelling following GBR.
- To correlate swelling with clinical parameters and regenerative outcomes.
Main Methods:
- A prospective study involving 25 participants undergoing GBR.
- Intraoral scans measured ridge width, height, and volume changes at multiple time points.
- Assessed parameters included soft tissue thickness, flap advancement, and bone gain.
Main Results:
- Swelling (width and height) peaked at 2 days post-surgery and returned to baseline by 7-14 days.
- Ridge volume increased by 19% at 2 days, with peak swelling preceding maximum wound opening.
- Post-GBR bone width correlated with gingival thickness, mucosal thickness, and flap advancement.
Conclusions:
- GBR-associated swelling peaks on postoperative day 2 and resolves within 14 days.
- Soft tissue thickness and flap advancement are significant factors influencing bone gain after GBR.

