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Updated: Jun 11, 2025

Sensing of Barrier Tissue Disruption with an Organic Electrochemical Transistor
Published on: February 10, 2014
Switched CMOS current source compared to enhanced Howland circuit for bio-impedance applications
Pablo Dutra da Silva1, Pedro Bertemes Filho1
1Electrical Engineering Department, State University of Santa Catarina, Mexico, Brazil.
A new Switching CMOS Current Source (SCMOSCS) offers superior performance for bio-impedance analysis (BIS) in wearable devices compared to the Enhanced Howland Current Source (EHCS). This innovation enables more accurate and efficient tissue analysis for disease diagnosis.
Area of Science:
- Biomedical Engineering
- Electrical Engineering
- Wearable Technology
Background:
- Bio-impedance Spectroscopy (BIS) is crucial for disease diagnosis and tissue analysis.
- Wearable healthcare devices require miniaturized, low-power CMOS integrated circuits for bio-impedance analysis.
- Existing current sources like the Enhanced Howland Current Source (EHCS) have limitations with broadband signals and power efficiency.
Purpose of the Study:
- To evaluate the performance of a novel Switching CMOS Current Source (SCMOSCS) against the EHCS for BIS applications.
- To assess the suitability of SCMOSCS for ultra-low power, high-performance wearable bio-impedance analysis.
- To compare current source capabilities using a Cole-skin model under various simulation conditions.
Main Methods:
- SPICE simulations were employed, including DC and AC sweeps and transient analysis.
- The performance of SCMOSCS was evaluated against EHCS using a Cole-skin model as a load.
- Key performance metrics such as output impedance, voltage swing, current consumption, and load capacity were measured.
Main Results:
- SCMOSCS achieved an output impedance exceeding 20 MΩ, a ±2.5 V output voltage swing from a 3.3 V supply, and supported a 10 kΩ load.
- SCMOSCS demonstrated significantly lower current consumption (275 μA) compared to EHCS (4.9 mA).
- EHCS exhibited a limited +1.5 V output voltage swing and a 3 kΩ load capacity.
Conclusions:
- SCMOSCS offers a more compatible and high-performance solution for bio-impedance analysis in wearable devices, especially with broadband signals like DIBS.
- The SCMOSCS design provides superior output voltage swing, load capacity, and power efficiency over EHCS.
- This advancement supports the development of next-generation, battery-powered wearable healthcare devices for enhanced diagnostics.
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