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Acute Angle Closure Glaucoma in a Patient With Jalili-Smith Syndrome
Sruthi Suresh1, Hafsa Z Zuberi2,1, Rahul Khandekar3
1Ophthalmology, University of Texas Southwestern Medical Center, Dallas, USA.
Cureus
|October 7, 2024
Summary
Jalili-Smith syndrome (JSS) patients can develop acute angle closure glaucoma. This case highlights novel optical coherence tomography angiography findings and surgical interventions in JSS.
Area of Science:
- Ophthalmology
- Genetics
- Dentistry
Background:
- Jalili-Smith syndrome (JSS) is a rare autosomal recessive disorder.
- It is characterized by oculo-dental anomalies, including cone-rod dystrophy and amelogenesis imperfecta.
- Consanguinity is a significant risk factor for JSS.
Observation:
- A 29-year-old Iranian male with JSS presented with acute angle closure glaucoma.
- Ocular manifestations included nystagmus, photophobia, cataracts, hyperopia, narrow-angle glaucoma, retinal thinning, and bull's eye maculopathy.
- Optical coherence tomography angiography (OCTA) findings were documented.
Findings:
- The patient underwent phacoemulsification (cataract surgery) and minimally invasive glaucoma surgeries (MIGS).
- This combination of interventions, along with OCTA findings, is novel in JSS patients.
- The case details the successful management of complex glaucoma in a JSS patient.
Implications:
- This report expands the understanding of JSS's ocular complications.
- It presents a unique surgical approach for managing glaucoma in JSS.
- Further research into JSS pathogenesis and treatment is warranted.
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