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Updated: Jun 11, 2025
Efficient Synthesis of Polyfunctionalized Benzenes in Water via Persulfate-promoted Benzannulation of α,β-Unsaturated Compounds and Alkynes
Published on: December 16, 2019
Alkoxyhydrosilane-facilitated cross-etherification reaction of secondary benzyl alcohol with aliphatic alcohol:
Toru Hashimoto1,2, Yakumo Matsunaga1, Yuki Okamura1
1Department of Applied Chemistry, Faculty of Engineering Sanyo-Onoda City University Sanyo-Onoda Yamaguchi 756-0884 Japan hashimototr@stf.teu.ac.jp.
Abstract:
Alkoxyhydorosilane is found to be an effective mediator for the cross-etherification reaction between two distinct alcohols, namely, a secondary benzyl alcohol and an aliphatic alcohol, providing the unsymmetrical dialkyl ethers in good-to-high yields. The reaction is also successfully applied to the lignin model compound, which is an important renewable non-fossil organic carbon source. Initial mechanistic studies indicated that the carbocation derived from benzyl alcohol was formed under the present reaction conditions.
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