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SalmoFree® Phage Additive Proves Its Safety for Laying Hens
Santiago Hernández Villamizar1, Juliana Arias Bonilla1,2, Álvaro Hugo Jaramillo3
1Ciencia y Tecnología de Fagos Sciphage SAS, Mosquera, Colombia.
PHAGE (New Rochelle, N.Y.)
|October 7, 2024
Summary
SalmoFree®, a bacteriophage cocktail, is safe for laying hens and shows potential for improving zootechnical parameters. This avian pathogen control method offers extended protection beyond the gut.
Area of Science:
- Poultry Science
- Microbiology
- Animal Health
Background:
- * Salmonella Gallinarum causes significant mortality in laying hens, impacting the poultry industry.
- * Current control methods include vaccines, antibiotics, probiotics, and disinfectants.
- * Bacteriophages offer a potential alternative for controlling S. Gallinarum colonization.
Purpose of the Study:
- * To evaluate the safety and efficacy of SalmoFree®, a bacteriophage cocktail, in laying hens.
- * To assess the impact of SalmoFree® on bird health and zootechnical parameters.
- * To determine the persistence and distribution of bacteriophages in treated birds.
Main Methods:
- * 276 laying hens were divided into control and treatment groups.
- * SalmoFree® was administered via drinking water over a 28-week period.
- * Safety and zootechnical parameters were monitored; phage presence was detected via PCR.
Main Results:
- * SalmoFree® showed no adverse effects on bird health or zootechnical parameters.
- * Trends indicated improvements in weight homogeneity (up to 19%), feed conversion (up to 68%), and egg weight (up to 2.7%).
- * Bacteriophages persisted in birds for 2-8 weeks and were detected in organs and eggshells, suggesting extra-intestinal protection.
Conclusions:
- * SalmoFree® is a safe bacteriophage product for laying hens.
- * It may provide additional benefits, including improved zootechnical performance.
- * Persistence of bacteriophages suggests prolonged protection against S. Gallinarum.
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