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Updated: Jun 11, 2025

The Establishment of a Murine Mandibular Molar Extraction Socket Healing Model
Published on: January 13, 2023
Alveolar regeneration of the post-extraction site with cortical deficiency using the Lamina Socket Sealing technique:
Pier C Passarelli1, Michele A Lopez1, Andrea Netti2
1Department of Head and Neck and Sensory Organs, Division of Oral Surgery and Implantology, Fondazione Policlinico Universitario A. Gemelli IRCCS - Università Cattolica del Sacro Cuore, Rome, Italy.
Purpose:
This retrospective observational study aims to evaluate the outcome of a new alveolar ridge preservation (ARP) technique, "Lamina Socket Sealing" (LSS) technique, using a porcine barrier.
Methods:
36 subjects with maxillary premolars to be extracted and extensive alveolar wall defects were enrolled and treated. Porcine-derived barriers and mesenchymal membrane were used to seal the extraction socket with alveolar particulate graft. The outcome variables were: radiographical bone changes and clinical outcomes.
Results:
36 subjects, 21 females and 15 males were treated. The change in mm (mean + SE) of horizontal ridge width from baseline to 4 months after surgery at the coronal level of the alveolus was +1.25 ± 0.20 mm (P< 0.05), mean level was +0.34 ± 0.1 mm (P< 0.05) and at the apical level was +0.08 ± 0.17 mm (P> 0.05) which was not statistically significant. The buccal and palatal height changes in mm (mean + SE) from baseline to 4 months after surgery were respectively 1.21 ± 0.17 mm for the buccal wall (P< 0.05) and 1.06 ± 0.24 mm for the palatal wall (P< 0.05). The bone volume of all sites allowed for the placement of the planned implants.
Clinical Significance:
The alveolar ridge preservation technique (Lamina Socket Sealing) using resorbable heterologous cortical lamina with flapless approach allowed not only the preservation of the damaged post-extraction socket, but also minimal ridge augmentation, according to the principles of guided bone regeneration.
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