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Utility of a synthetic hybrid-scale fiber matrix in the management of pyoderma gangrenosum: a case study
Kaitlyn J Loesel1, Blake E Pritchett1, Alexander Schultz1
1Podiatric Medicine and Surgery, Department of Orthopedics, University of Louisville, Louisville, KY.
Background:
Pyoderma gangrenosum (PG) is a rare skin condition that is challenging for both patients and physicians alike. It is extremely painful and can become debilitating for many patients. PG has a mortality rate of 16% at 8 years, and patients with PG have a threefold risk of death compared to the general population. Currently, the management of PG is not standardized and is somewhat experimental as these wounds are prone to pathergy.
Case Report:
A single patient diagnosed with PG of both lower extremities was successfully treated with a protocol that included serial wound debridement with a sterile scrub brush and hydrodebridement followed by application of a synthetic hybrid-scale fiber matrix (SHSFM) dressing. The patient's wounds successfully healed and the resolution was maintained at 2 years, at which time the patient was discharged from the clinic.
Conclusion:
To the authors' knowledge, this is the first study reporting the use of SHSFM as a primary treatment option for PG.
