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Published on: January 24, 2025
Syphilis and pregnancy
Geraldo Duarte1, Patrícia Pereira Dos Santos Melli2, Angélica Espinosa Miranda3
1Faculdade de Medicina de Ribeirão Preto Universidade de São Paulo Ribeirão PretoSP Brazil Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
Congenital syphilis rates are rising despite effective treatments, challenging public health. Multifactorial failures in education, policy, and quality control hinder effective management of syphilis in pregnant women.
Area of Science:
- Obstetrics and Gynecology
- Infectious Diseases
- Public Health
Background:
- Congenital syphilis remains a significant challenge for maternal and child health services globally.
- Rising syphilis rates in the general population directly correlate with increased congenital syphilis cases, posing a public health concern.
- Despite being notifiable diseases, syphilis and congenital syphilis control measures have not yet reduced their incidence.
Purpose of the Study:
- To analyze the multifactorial reasons behind the persistent failure to control congenital syphilis.
- To highlight deficiencies in education, professional training, and quality control in antenatal and postnatal care for syphilis.
- To address the challenges associated with the effective treatment of syphilis in pregnant women, particularly concerning benzathine penicillin.
Main Methods:
- Review of scientific evidence on congenital syphilis control and treatment protocols.
- Analysis of factors contributing to treatment failure and quality control lapses.
- Examination of public health policies and educational strategies related to syphilis prevention and management.
Main Results:
- Failure to control congenital syphilis is multifactorial, stemming from educational deficits and inadequate quality control in healthcare.
- Benzathine penicillin is the sole recommended treatment for syphilis in pregnant women, yet fear of anaphylaxis impedes its administration.
- Despite published protocols, high-frequency failures in treating syphilis during pregnancy indicate systemic quality control issues.
Conclusions:
- Effective control of congenital syphilis requires addressing educational gaps and strengthening quality assurance in antenatal care and follow-up.
- Overcoming the fear of anaphylaxis and ensuring consistent adherence to treatment protocols are crucial for managing syphilis in pregnant women.
- A comprehensive approach involving education, policy enforcement, and rigorous quality control is necessary to reduce congenital syphilis rates.
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