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Updated: Jun 11, 2025

Combined Intravital Microscopy and Contrast-enhanced Ultrasonography of the Mouse Hindlimb to Study Insulin-induced Vasodilation and Muscle Perfusion
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Uncommon Muscle Complications in Diabetes: A Case Report on Diabetic Muscle Infarction.

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  • 1Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education & Research, Wardha, IND.

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|October 9, 2024
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Summary

Diabetic muscle infarction (DMI) is a rare diabetes complication causing leg pain and swelling. Early diagnosis and management are key to preventing severe outcomes in diabetic patients.

Keywords:
acute muscle paindiabetes mellitus complicationsdiabetic muscle infarctiondual antiplatelethemodialysismri diagnosismuscle necrosis

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Area of Science:

  • Endocrinology
  • Musculoskeletal Medicine

Background:

  • Diabetic muscle infarction (DMI) is a rare but serious complication of diabetes mellitus (DM).
  • It typically presents with acute muscle pain and swelling, predominantly in the lower extremities.
  • Prompt recognition and management are crucial for preventing further complications.

Observation:

  • A 54-year-old male with type 2 DM and hypertension presented with severe left calf pain, edema, and tenderness.
  • Investigations revealed muscle injury and inflammation.
  • MRI confirmed DMI with characteristic muscle inflammation.

Findings:

  • The patient received hemodialysis, dual antiplatelet therapy, analgesics, and strict blood glucose control.
  • Lifestyle modifications, medication adherence, and avoiding excessive physical activity were advised.
  • Regular follow-up was planned for monitoring and treatment adjustment.

Implications:

  • This case highlights the importance of considering DMI in diabetic patients with acute leg pain.
  • Early diagnosis and appropriate management are essential for improving patient outcomes.
  • Clinicians should maintain a high index of suspicion for DMI for timely intervention.