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Related Concept Videos

Hiatal Hernia01:25

Hiatal Hernia

A hiatal hernia is the abnormal protrusion of the stomach or other abdominal organs through the esophageal hiatus of the diaphragm into the thoracic cavity.Normally, the gastroesophageal junction (GEJ) lies below the diaphragm and is supported by the phrenoesophageal membrane, the diaphragmatic crura, and connective tissues. Weakening of these structures—due to aging, congenital defects like a short esophagus, or increased intra-abdominal pressure from coughing, obesity, pregnancy, or heavy...

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Updated: May 12, 2026

Laparoscopic Repair of Para-Esophageal Hernia Using Absorbable Biosynthetic Mesh
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Ventral Hernia Repair With a Hybrid Absorbable-permanent Preperitoneal Mesh.

Matthew I Goldblatt1, Matthew Reynolds2, Carl R Doerhoff3

  • 1Department of Surgery, Medical College of Wisconsin, Milwaukee, WI.

Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
|October 9, 2024
PubMed
Summary
This summary is machine-generated.

The GORE SYNECOR Preperitoneal Biomaterial (PRE device) shows safety and effectiveness in complex ventral hernia repairs. This permanent mesh with a bioabsorbable scaffold resulted in low complication and recurrence rates.

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Area of Science:

  • Surgical Innovation
  • Biomaterials Science
  • Hernia Surgery

Background:

  • Ventral hernia repair often involves permanent mesh prosthetics.
  • Challenges include mesh-related complications and hernia recurrence.
  • New biomaterials aim to improve outcomes by combining different material properties.

Purpose of the Study:

  • To evaluate the safety and clinical outcomes of the GORE SYNECOR Preperitoneal Biomaterial (PRE device) for ventral hernia repair.
  • To assess device and procedure endpoints, as well as patient-reported outcomes.
  • To determine the efficacy of this novel mesh in complex hernia cases.

Main Methods:

  • Multicenter retrospective review of patients undergoing ventral hernia repair with the PRE device.
  • Analysis of device/procedure endpoints and patient-reported outcomes.
  • Minimum follow-up of 1 year post-enrollment.

Main Results:

  • 148 patients included, with a mean age of 56 years; 66.2% had VHWG grade 2 classification.
  • Robotic (53.4%) and open (41.9%) approaches were common, with all meshes placed extraperitoneally.
  • Low rates of procedure-related adverse events (8.8%), surgical site infections (4.8%), and surgical site occurrences (3.4% at 12 months) were observed. No hernia recurrences were reported.

Conclusions:

  • The PRE device, combining absorbable and permanent mesh features, is safe and effective for complex ventral hernia repair.
  • Retromuscular placement demonstrated reduced wound complications and recurrence rates compared to single-material meshes.
  • This biomaterial offers a promising solution for challenging hernia cases.