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Related Concept Videos

Computed Tomography01:10

Computed Tomography

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Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
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Tandem Mass Spectrometry01:21

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Tandem mass spectrometry is a technique that uses multiple mass analyzers in series to obtain a higher selectivity and signal-to-noise ratio for the analyte. Instruments with multiple analyzers separated by an interaction cell enable secondary fragmentation and selected study of the fragment ions.
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Inductively Coupled Plasma Atomic Emission Spectroscopy: Instrumentation01:26

Inductively Coupled Plasma Atomic Emission Spectroscopy: Instrumentation

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Inductively coupled plasma (ICP) is the common plasma source used in atomic emission spectroscopy (AES), a technique that detects and analyzes various elements in a sample. This method is often called inductively coupled plasma atomic emission spectroscopy (ICP-AES).
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Atomic Emission Spectroscopy: Instrumentation01:22

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The instrumentation of atomic emission spectrometry (AES) involves various components, including atomization devices that convert samples into gas-phase atoms and ions. There are two main types of atomization devices: continuous and discrete atomizers.  Continuous atomizers, like plasmas and flames, introduce samples in a constant stream, while discrete atomizers inject individual samples using syringes or autosamplers. The most common discrete atomizer is the electrothermal atomizer.
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Mass Spectrometers01:16

Mass Spectrometers

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This lesson details the instrumentation of a mass spectrometer—a physical instrument to perform mass spectrometry on analyte molecules and record the characteristic mass spectra. This is achieved via three chief functions:
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Updated: Jun 11, 2025

Using Synchrotron Radiation Microtomography to Investigate Multi-scale Three-dimensional Microelectronic Packages
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Evolving SPECT-CT technology.

Kathy P Willowson1,2, Dale L Bailey1,3

  • 1Department of Nuclear Medicine, Royal North Shore Hospital, Sydney, NSW 2065, Australia.

The British Journal of Radiology
|October 9, 2024
PubMed
Summary
This summary is machine-generated.

Advancements in single photon emission computed tomography (SPECT)/X-ray computed tomography (CT) technology enhance its clinical utility, particularly in theranostics and biodistribution studies. Despite challenges, SPECT/CT remains a valuable asset for radionuclide therapy planning and evaluation.

Keywords:
CTSPECTimaging technology

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Area of Science:

  • Medical Imaging Technology
  • Nuclear Medicine
  • Radiopharmaceutical Therapy

Background:

  • Rapid advancements in both hardware and software have significantly propelled single photon emission computed tomography (SPECT)/X-ray computed tomography (CT) technology.
  • Clinical demand and the growing field of theranostics have been key drivers for these technological developments.
  • Emerging applications include whole-body quantitative reconstructions and digital detector technologies.

Purpose of the Study:

  • To review recent developments in SPECT/CT technology.
  • To discuss the clinical impact of these advancements.
  • To highlight the expanding role of SPECT/CT in theranostics and radionuclide therapy.

Main Methods:

  • Review of technological advancements in SPECT/CT hardware and software.
  • Analysis of clinical applications, focusing on theranostics, biodistribution, and dosimetry.
  • Comparison of SPECT/CT capabilities with other imaging modalities like PET.

Main Results:

  • SPECT/CT technology has achieved comparability with PET in several aspects due to innovations like whole-body quantitative reconstructions and digital detectors.
  • The technology plays a crucial role in biodistribution and dosimetry studies for planning and evaluating radionuclide therapy.
  • Despite limitations in spatial resolution and sensitivity, SPECT/CT offers unique advantages for imaging long-lived radioisotopes and multi-tracer studies.

Conclusions:

  • SPECT/CT is a valuable clinical tool, enhanced by technological progress.
  • Its capabilities in biodistribution, dosimetry, and theranostics are expanding.
  • The accessibility and unique imaging opportunities make SPECT/CT indispensable in modern nuclear medicine.