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ARTnet Perspectives and Contributions to Theranostics.

Roslyn J Francis1,2,3, Dale L Bailey4,5,6, Kathy Willowson4

  • 1Department of Nuclear Medicine, Royal Brisbane and Women's Hospital, Brisbane, Australia.

World Journal of Nuclear Medicine
|November 12, 2025
PubMed
Summary

The Australasian Radiopharmaceutical Trials Network (ARTnet) enhances cancer theranostics research. ARTnet facilitates high-quality, multicenter clinical trials for radiopharmaceuticals, advancing patient care and treatment approvals.

Keywords:
clinical trialsharmonizationoncologyradiopharmaceuticalstheranostics

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Area of Science:

  • Nuclear Medicine
  • Oncology
  • Clinical Pharmacology

Background:

  • Theranostics offers novel cancer treatment strategies.
  • Multicenter clinical trials with radiopharmaceuticals are crucial for validating new therapies.
  • Ensuring data quality in these trials is paramount for clinical adoption.

Purpose of the Study:

  • To describe the establishment, operations, and impact of the Australasian Radiopharmaceutical Trials Network (ARTnet).
  • To highlight ARTnet's role in advancing theranostics research in Australia.
  • To emphasize the importance of clinical trials networks in theranostics development.

Main Methods:

  • Development and operationalization of a multidisciplinary clinical trials network (ARTnet).
  • Facilitation of prospective, multicenter clinical trials involving radiopharmaceuticals.
  • Implementation of quality activities and engagement strategies to ensure reliable data.

Main Results:

  • ARTnet has supported impactful clinical trials over the past decade.
  • Australia has played a significant role in the clinical translation of theranostics.
  • ARTnet's efforts have contributed to regulatory approvals and international healthcare funding.

Conclusions:

  • ARTnet is a key facilitator for high-quality radiopharmaceutical clinical trials in Australia.
  • The network's activities are vital for the advancement of theranostics.
  • ARTnet's focus on quality and collaboration supports the global progression of theranostic cancer care.