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Related Concept Videos

Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

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Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
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Portal hypertension is an increase in blood pressure within the portal venous system. Normally, this pressure is less than 5 mmHg. It is considered clinically significant when it rises above 10 mmHg. At this threshold, complications from altered blood flow and venous congestion emerge.EtiologyPortal hypertension arises from conditions that impede blood flow through the liver. The most common cause is cirrhosis, in which chronic liver injury leads to fibrotic scarring. This fibrosis narrows or...
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Related Experiment Video

Updated: May 7, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
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Systemic Amyloidosis Presenting as Budd-Chiari Syndrome: A Case Report.

Naman Lodha1, Samarth Bhat K S1, Kartikeya Mathur2

  • 1Department of General Medicine, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.

Middle East Journal of Digestive Diseases
|October 10, 2024
PubMed
Summary

Systemic amyloidosis, a protein misfolding disorder, can rarely manifest as Budd-Chiari syndrome (BCS), a liver vein obstruction. This case highlights the importance of considering amyloid light chain amyloidosis in BCS diagnosis.

Area of Science:

  • Hepatology
  • Nephrology
  • Cardiology
  • Hematology
Keywords:
Budd-Chiari syndromeHypercoagulabilityInfiltrative liver diseaseSystemic amyloidosis

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Background:

  • Budd-Chiari syndrome (BCS) involves hepatic venous outflow obstruction, often linked to hypercoagulable states.
  • Systemic amyloidosis is characterized by misfolded protein deposition causing end-organ damage and coagulation abnormalities.
  • Amyloidosis frequently presents with bleeding diathesis, complicating its clinical picture.