A NH2-Cu-MOF for promising antibacterial application
Zhenxi Li1, Jing Cheng2, Zhixin Xie3
1Department of Basic Medicine, Quanzhou Medical College, Quanzhou, 362000, Fujian, China. Q66076806aq@126.com.
Abstract:
A copper-based metal-organic framework named NH2-Cu-MOF has been synthesized and utilized as an effective broad-spectrum antimicrobial material in this article. The obtained NH2-Cu-MOF exhibits satisfying antibacterial activity against both gram-positive bacteria (S. aureus and S. epidermidis) and gram-negative bacteria (E. coli and K. peneumoniae). Additionally, the biocompatibility of this NH2-Cu-MOF has been validated through animal studies, showing no significant adverse effects, thereby confirming its high biocompatibility. These findings prove that NH2-Cu-MOF has positive effects upon the treatment of bacteria-infected wounds, which holds great potential to be applied in biochemistry field.
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