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Published on: March 11, 2016
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The scanning CONfoCal Ophthalmoscopy foR DIAbetic eye screening (CONCORDIA) study paper 2
Peter H Scanlon1,2,3, Marta Gruszka-Goh4,5, Ushna Javed4
1Gloucestershire Retinal Research Group (GRRG), Cheltenham General Hospital, Cheltenham, UK. p.scanlon@nhs.net.
Eye (London, England)
|October 11, 2024
Summary
The Eidon Scanning Confocal Ophthalmoscope (SCO) camera shows promise for diabetic eye screening. Staged mydriasis improved image assessment, indicating its potential safety and efficacy in Diabetic Eye Screening Programmes (DESP).
Area of Science:
- Ophthalmology
- Medical Imaging
- Diabetic Retinopathy Screening
Background:
- Diabetic retinopathy is a leading cause of blindness.
- Early detection through screening programmes is crucial.
- Ophthalmoscopy is a key diagnostic tool.
Purpose of the Study:
- To evaluate the safety and efficacy of the Eidon white light 60-degree field Scanning Confocal Ophthalmoscope (SCO) camera.
- To assess the utility of staged mydriasis with the Eidon SCO camera in a Diabetic Eye Screening Programme (DESP).
Main Methods:
- A prospective study involving 1015 patients with diabetes.
- Comparison of non-mydriatic and mydriatic SCO images with digital photography (reference standard).
- Staged mydriasis was employed, with SCO imaging before pupil dilation.
Main Results:
- Sensitivity for any retinopathy was 97.5%; specificity was 82.3%.
- Sensitivity for referable retinopathy was 92.7%; specificity was 85.4%.
- Unassessable images decreased from 4.2% without mydriasis to 1.7% with mydriasis.
Conclusions:
- The Eidon SCO camera with staged mydriasis demonstrates promising performance in DESP.
- Further research is needed in non-Caucasian populations and cost-effectiveness analyses.
- The camera appears safe and effective for diabetic retinopathy screening.
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