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The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
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Plaque psoriasis with renal dysfunction successfully treated with ixekizumab

Xinyu Zhu1, Xiaoyuan Pan1, Zhengbang Dong1

  • 1Department of Dermatology, Zhongda Hospital, Southeast University, Nanjing, China.

Hemodialysis International. International Symposium on Home Hemodialysis
|October 13, 2024
PubMed

Psoriasis is an immune-mediated chronic inflammatory skin disease and chronic kidney disease is one of the common comorbidities of psoriasis. Ixekizumab, a humanized IgG4 monoclonal antibody, has been approved for the treatment of moderate-to-severe plaque psoriasis in recent years. However, ixekizumab has not been studied in a population of patients with renal insufficiency. We report two cases of plaque psoriasis patients with renal dysfunction successfully treated with ixekizumab without dose reduction，which experience no side effects and does not cause further kidney injury.

Keywords:
case reportchronic kidney diseaseixekizumabperitoneal dialysisplaque psoriasis

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