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Baseline Characteristics and Clinical Insights from the ARTEMIS Registry: A Comprehensive Study of Peripartum

Meral Kayıkçıoğlu1, Murat Biteker2, Ferit Onur Mutluer3

  • 1Department of Cardiology, Ege University Faculty of Medicine, Izmir, Türkiye.

Turk Kardiyoloji Dernegi Arsivi : Turk Kardiyoloji Derneginin Yayin Organidir
|October 14, 2024
PubMed

Insights

Peripartum Cardiomyopathy (PPCM) affects women during late pregnancy or postpartum. The ARTEMIS registry in Türkiye found common symptoms, reliance on echocardiography, and a 5.1% mortality rate, emphasizing registry importance for rare disease management.

Area of Science:

  • Cardiology
  • Obstetrics
  • Public Health

Background:

  • Peripartum Cardiomyopathy (PPCM) is a rare, life-threatening heart condition affecting women in late pregnancy or postpartum.
  • Understanding PPCM's characteristics and outcomes in specific populations is crucial for effective management.

Purpose of the Study:

  • To investigate the clinical features, diagnostic approaches, treatment strategies, and outcomes of Peripartum Cardiomyopathy (PPCM) in Turkish patients.
  • To provide insights into PPCM management within Türkiye through the ARTEMIS registry.

Main Methods:

  • Retrospective enrollment of 293 patients diagnosed with PPCM within the last five years across 44 cardiology centers in Türkiye.
  • Data collection included demographics, clinical presentation, diagnostic methods (primarily echocardiography), treatments, and outcomes.
  • Exclusion criteria included age under 18 and pre-existing cardiac conditions.

Main Results:

  • The study population (293 patients) was predominantly aged 25-35, with dyspnea and palpitations as common symptoms, often diagnosed postpartum.
  • Echocardiography was the primary diagnostic tool; advanced imaging use was limited.
  • Common treatments included beta-blockers (97.8%) and ACE inhibitors (71.3%), with bromocriptine used in severe cases (6.9%). A 5.1% mortality rate was observed.

Conclusions:

  • The ARTEMIS registry offers valuable data on PPCM management in Türkiye.
  • Findings highlight the need for enhanced healthcare provider and patient education regarding PPCM.
  • The study underscores the critical role of national registries in advancing the understanding and improving outcomes for rare cardiovascular diseases.
Abstract

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