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Biotransformation of Geraniol to Geranic Acid Using Fungus Mucor irregularis IIIMF4011
Haseena Shafeeq1,2, Bashir Ahmad Lone1,2, Ananta Ganjoo1,2
1CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, India.
Abstract:
Geraniol is an important component in essential oils of aromatic plants such as lemongrass, rosa grass, and many others. It can be converted to different high-value products by using microbes/enzymes. The present study aims at the isolation and screening of microbes showing efficient production of geranic acid (a high-value product) from geraniol (a low-value monoterpene). Mucor irregularis IIIMF4011, isolated from the soil sample of Cymbopogon citratus (Lemongrass), showed biotransformation of geraniol to geranic acid. After optimization of reaction parameters, 97-100% conversion of geraniol to geranic acid was obtained after 72 h of incubation at 28 °C. Furthermore, the biotransformation reaction was also carried out in a 3 L fermentor (working volume 1.5 L), and 98.89% conversion was observed. Therefore, an efficient process of geranic acid production using M. irregularis IIIMF4011 was developed.
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