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A 6-Month Follow-Up Comparative Study of Single-Step Transepithelial Photorefractive Keratectomy (Trans-PRK) Using

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Summary

Epithelial thickness customization in Transepithelial Photorefractive Keratectomy (Trans-PRK) did not significantly alter refractive or aberrometry outcomes. Corneal densitometry changes were observed but did not impact visual acuity in either group.

Keywords:
Trans-PRKcorneal aberrometrycorneal densitometrycorneal epithelial thicknesscorneal refractive surgery

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Area of Science:

  • Ophthalmology
  • Corneal Surgery
  • Refractive Surgery

Background:

  • Transepithelial Photorefractive Keratectomy (Trans-PRK) is a refractive surgery technique.
  • Epithelial thickness can influence surgical outcomes.
  • Customizing epithelial ablation may potentially improve results.

Purpose of the Study:

  • To compare corneal aberrometry, densitometry, and refractive outcomes of Trans-PRK.
  • To evaluate the impact of epithelial thickness customization versus standard thickness.

Main Methods:

  • Prospective, randomized controlled study involving 108 eyes.
  • Trans-PRK performed using WaveLight EX500 laser.
  • Groups: standard epithelial thickness (control) vs. customized thinnest point.
  • Measurements: visual acuity, refraction, aberrometry, corneal densitometry via MS-39 OCT.

Main Results:

  • No significant differences in refractive or aberrometry outcomes between groups.
  • Both groups showed increased higher-order and spherical aberrations post-surgery.
  • Corneal densitometry decreased in the anterior cornea and increased in the posterior cornea in both groups.
  • Epithelial ablation thickness was similar between groups.

Conclusions:

  • Epithelial thickness customization in Trans-PRK does not significantly affect refractive or aberrometry outcomes.
  • Observed changes in corneal densitometry did not negatively impact visual acuity.
  • Standard and customized Trans-PRK yield comparable results regarding visual function and optical quality.