Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Asymmetric Lipid Bilayer

Asymmetric Lipid Bilayer

Biological membranes show uneven distribution of different types of lipids in the inner and outer layers, resulting in transverse asymmetric membranes. The treatment of the erythrocyte membrane with the enzyme phospholipase confirmed the asymmetric nature of the lipid bilayer. The enzyme hydrolyzes lipids into fatty acids and hydrophilic groups. The phospholipase acts only on the outer layer of the membrane, while the inner layer remains intact. The phospholipase treatment resulted in 80%...

Bioavailability Enhancement: Drug Permeability Enhancement

Bioavailability Enhancement: Drug Permeability Enhancement

After oral administration, poor permeability often limits the rate at which drugs are absorbed through the intestinal epithelium. Enhancing drug permeability is crucial for effective therapy, and several strategies have been developed to overcome this challenge.One effective strategy involves the use of lipid-based formulations. These formulations enhance dissolution and solubility, targeting physiological mechanisms to increase drug absorption. This includes stimulating bile salt secretion,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

DNA cube-gated ratiometric ECL/SERS biosensor for APE1 via HCR-driven interfacial reconstruction.

Biosensors & bioelectronics·2026

Same author

Dual-mode ECL/SERS ratiometric sensing of 3CLpro via enzyme-gated, entropy-driven DNA assembly on CsPbBr₃@PDA@Au.

Colloids and surfaces. B, Biointerfaces·2026

Same author

Self-validated SARS-CoV-2 detection via an automated DNA molecular machine-regulated ECL/SERS signal switching platform.

Biosensors & bioelectronics·2026

Same author

Aptakiss-guided CRISPR/Cas13a signal amplification for ultrasensitive FEN1 detection using CsPbBr<sub>3</sub>@PDA@AuNPs-based electrochemiluminescence platform.

Biosensors & bioelectronics·2026

Same author

Cube-track encoded dual-mode ECL/SERS biosensor for ultrasensitive NF-κB p50 detection via transcription-DSN cascade.

Biosensors & bioelectronics·2026

Same author

Development of machine perfusion strategies for liver support and beyond.

Journal of advanced research·2026

Search research articles

Related Experiment Video

Updated: Jun 22, 2026

Preparation and Characterization of Nanoliposomes for the Entrapment of Bioactive Hydrophilic Globular Proteins

Preparation and Characterization of Nanoliposomes for the Entrapment of Bioactive Hydrophilic Globular Proteins

Published on: August 31, 2019

Developing Cell-Membrane-Associated Liposomes for Liver Diseases.

Dongxue Ge¹, Ran An¹, Lingling Xue¹

¹Division of Hepatobiliary and Transplantation Surgery, Department of General Surgery, Nanjing Drum Tower Hospital, Clinical College of Nanjing University of Chinese Medicine, Nanjing 210008, China.

|October 15, 2024

Summary

This summary is machine-generated.

Cell membrane-associated liposomes offer promising drug delivery for liver diseases. Further research is needed to optimize their use and overcome clinical challenges in treating hepatic pathologies.

Keywords:

Application Cell membrane Delivery strategy Interaction Liposome Liver disease Preparation Targeting

More Related Videos

Microfluidic Production of Lysolipid-Containing Temperature-Sensitive Liposomes

Microfluidic Production of Lysolipid-Containing Temperature-Sensitive Liposomes

Published on: March 3, 2020

Preparation, Administration, and Assessment of In Vivo Tissue-Specific Cellular Uptake of Fluorescent Dye-Labeled Liposomes

Preparation, Administration, and Assessment of In Vivo Tissue-Specific Cellular Uptake of Fluorescent Dye-Labeled Liposomes

Published on: July 30, 2020

Related Experiment Videos

Last Updated: Jun 22, 2026

Preparation and Characterization of Nanoliposomes for the Entrapment of Bioactive Hydrophilic Globular Proteins

Preparation and Characterization of Nanoliposomes for the Entrapment of Bioactive Hydrophilic Globular Proteins

Published on: August 31, 2019

Microfluidic Production of Lysolipid-Containing Temperature-Sensitive Liposomes

Microfluidic Production of Lysolipid-Containing Temperature-Sensitive Liposomes

Published on: March 3, 2020

Preparation, Administration, and Assessment of In Vivo Tissue-Specific Cellular Uptake of Fluorescent Dye-Labeled Liposomes

Preparation, Administration, and Assessment of In Vivo Tissue-Specific Cellular Uptake of Fluorescent Dye-Labeled Liposomes

Published on: July 30, 2020

Area of Science:

Biomedical Engineering
Drug Delivery Systems
Hepatology

Background:

Liver diseases are increasing, with limited efficacy of current pharmacological treatments.
Liposomes enhance drug delivery to targeted sites, improving therapeutic effectiveness.
Cell membrane-associated liposomes show potential but require deeper understanding of their binding mechanisms.

Purpose of the Study:

To review cell membrane-associated liposomes for liver disease treatment.
To summarize their composition, types, structure, and drug delivery strategies.
To discuss clinical applications, challenges, and future prospects.

Main Methods:

Comprehensive literature review on cell membrane-associated liposomes.
Analysis of their structure, composition, and drug delivery mechanisms.
Evaluation of clinical applications and challenges in treating liver diseases.

Main Results:

Cell membrane-associated liposomes offer enhanced drug targeting for liver pathologies.
Various strategies exist for drug delivery using these liposomes.
Significant potential benefits are identified, alongside existing clinical challenges.

Conclusions:

Cell membrane-associated liposomes show promise for improving liver disease treatment.
Further research is essential to optimize their utilization and address clinical hurdles.
Future development directions are outlined for enhanced therapeutic outcomes.