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Updated: Jul 6, 2026

An Orthotopic Model of Murine Bladder Cancer

An Orthotopic Model of Murine Bladder Cancer

Published on: February 6, 2011

[Breast cancer metastases in the urinary bladder].

Samitha Vasantharajan¹, Nicolai Wessel², Inger Thune³

¹Avdeling for urologi, og, Avdeling for gastro- og barnekirurgi, Oslo universitetssykehus.

Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke

|October 15, 2024

Summary

Distant breast cancer metastasis to the bladder is rare. This case highlights diagnostic challenges, especially when kidney stones are present, complicating the detection of bladder tumors.

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Magnetic Resonance Imaging Assessment of Carcinogen-induced Murine Bladder Tumors

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Published on: March 29, 2019

Area of Science:

Oncology
Urology
Pathology

Background:

Bladder cancer typically originates from urothelial cells.
Locoregional metastases to the bladder can occur.
Distant metastases to the bladder are uncommon.

Observation:

An elderly woman with a history of breast cancer presented with hematuria and night sweats.
Initial evaluation suggested kidney stones, masking the underlying pathology.
Elevated tumor markers (MUC1/CA 15-3) and persistent hematuria prompted further investigation.

Findings:

Histological examination of bladder lesions revealed metastatic infiltrating lobular carcinoma from the breast.
Concurrent kidney stones presented a diagnostic challenge, mimicking urological symptoms.

Implications:

This case underscores the importance of considering distant metastases in patients with a history of cancer, even with seemingly unrelated symptoms.
Advanced imaging and thorough urological workup are crucial for diagnosing rare bladder metastases.
The presence of confounding conditions, like kidney stones, can delay diagnosis and necessitate a high index of suspicion for metastatic disease.