1,3-Bishomocubane: a kinetic rock, a thermodynamic powerhouse and a compelling chiral synthetic scaffold
Gangavara L Tejashree1, Amrish Dave1, Neeraj Kumbhakarna2
1Department of Chemistry, Indian Institute of Technology Bombay, Mumbai 400 076, India. irishi@iitb.ac.in.
Abstract:
Over the last several decades, saturated polycyclic cage compounds have remained a point of interest for organic chemists because of their unique characteristics and reactivity. For the first time, a detailed analysis of the synthesis, properties and transformations of 1,3-bishomocubanes, which fall under the rare category of chiral cage compounds, is provided in this article. This review which also includes the authors' work in this area over the last decade is expected to serve as a valuable resource for chemists interested in the fascinating chemistry and properties of polycyclic cage compounds.
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