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Predicting faller status in persons with multiple sclerosis using the Multiple Sclerosis Walking Scale-12.

Caterina Abate1, Elizabeth S Gromisch2, Marc Campo1

  • 1Mercy University, 555 Broadway, Dobbs Ferry, NY, USA.

Multiple Sclerosis and Related Disorders
|October 15, 2024
PubMed
Summary
This summary is machine-generated.

The Multiple Sclerosis Walking Scale (MSWS-12) can identify individuals with multiple sclerosis (MS) who are at higher risk of falling. A score of 46% or higher on the MSWS-12 indicates an increased likelihood of being a faller.

Keywords:
FallsMSWS-12Multiple SclerosisScreening ToolsWalking

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Area of Science:

  • Neurology
  • Rehabilitation Science
  • Clinical Assessment

Background:

  • Persons with multiple sclerosis (PwMS) face a heightened risk of falls.
  • Effective screening tools are crucial for identifying PwMS prone to falls.
  • This study aimed to validate the MSWS-12 as a fall screening tool.

Purpose of the Study:

  • To establish a cut-off score for the MSWS-12 to identify fallers among PwMS.
  • To assess the predictive accuracy of the MSWS-12 for faller status.
  • To evaluate the MSWS-12's predictive ability while controlling for confounding factors.

Main Methods:

  • 171 PwMS completed the MSWS-12 and reported falls in the past six months.
  • Fallers were defined as reporting one or more falls.
  • Receiver-operating-characteristic (ROC) curve analysis determined classification accuracy (AUC).
  • Logistic regression controlled for age, gender, BMI, disease duration, and fatigue.

Main Results:

  • The MSWS-12 demonstrated fair classification accuracy for fallers (AUC = 0.74).
  • A cut-off score of ≥ 46% yielded 76.1% sensitivity and 64.6% specificity.
  • The MSWS-12 score (aOR: 3.77) and fatigue (aOR: 1.11) significantly predicted faller status.

Conclusions:

  • PwMS scoring ≥ 46% on the MSWS-12 are more likely to be fallers.
  • The MSWS-12 shows potential as a valuable screening tool for fall risk in MS.
  • Clinical judgment and other assessments can enhance the utility of the MSWS-12.