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Updated: Jun 10, 2025

A Freeze-Thawing Method to Prepare Chitosan-Polyvinyl alcohol Hydrogels Without Crosslinking Agents and Diflunisal Release Studies
Published on: January 14, 2020
Preparation of dandelion flower extract-based polyvinyl alcohol-chitosan-dandelion-CuNPs composite gel for efficient
Yue Wang1, Tingting Zhang1, Meizi Huang2
1School of Pharmacy & Biological and Food Engineering, Changzhou University, Changzhou 213164, China.
Abstract:
A multifunctional composite gel with efficient bacteriostatic and dye adsorption properties was prepared using polyvinyl alcohol, chitosan, and soybean isolate protein as carriers, CuNPs prepared by green reduction of dandelion extract as bacteriostatic agent, and glutaraldehyde as cross-linking agent. The composite gel showed good inhibition capacity of Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa with the diameter of inhibition zone of 27.0-28.3 mm by agar diffusion method. The composite gel antibacterial rate remained above 90 % after 14 days of preparation. After 6 times reuse of composite gel in water, the antibacterial rate remained above 90 %, proving its good stability and reusability. Adding dandelion extract and CuNPs greatly improved the gel antioxidant property, acquiring free radical scavenging rate at 95.6 %. This composite gel had good biocompatibility and adsorption performance, and the maximum adsorption amount of methylene blue and methyl orange was 40.36 mg/g and 41.81 mg/g, respectively. To sum up, the green composition of composite gel has good antimicrobial performance and high dye adsorption, which holds significant promising for treating the water body pollution and protecting the environment. To build cost-effective antibacterial and dye adsorption process on a large-scale, in-depth exploration about this topic is still needed to develop.

