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Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
126
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation01:30

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation

146
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
146
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

147
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
147
Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

162
Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
162
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

323
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
323
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

397
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
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Related Experiment Video

Updated: Jun 10, 2025

Diagnosis of Hirschsprung's Disease by Immunostaining Rectal Suction Biopsies for Calretinin, S100 Protein and Protein Gene Product 9.5
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Diagnosis of Hirschsprung's Disease by Immunostaining Rectal Suction Biopsies for Calretinin, S100 Protein and Protein Gene Product 9.5

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Hirschsprung-associated enterocolitis: a comprehensive review.

Ioannis A Ziogas1, Korah P Kuruvilla1, Ming Fu1

  • 1Division of Pediatric Surgery, Department of Surgery, Children's Hospital Colorado, Aurora, Colorado, USA.

World Journal of Pediatric Surgery
|October 16, 2024
PubMed
Summary

Hirschsprung-associated enterocolitis (HAEC) is a serious complication of Hirschsprung disease. Understanding its risk factors, pathogenesis, and management is crucial for improving patient outcomes.

Keywords:
Colorectal SurgeryRectal Diseases

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Area of Science:

  • Gastroenterology
  • Pediatric Surgery
  • Immunology

Background:

  • Hirschsprung-associated enterocolitis (HAEC) is a severe complication in patients with Hirschsprung disease.
  • It is the primary cause of mortality and significant morbidity in this population.

Purpose of the Study:

  • To provide a comprehensive review of HAEC.
  • Elaborate on risk factors, pathogenesis, diagnosis, treatment, and prevention strategies.

Main Methods:

  • Literature review of existing studies on HAEC.
  • Synthesis of information regarding pathophysiology, clinical presentation, and management.

Main Results:

  • HAEC involves dysmotility, dysbiosis, intestinal barrier dysfunction, and immune impairment.
  • Clinical signs include fever, abdominal distension, lethargy, vomiting, and diarrhea.

Conclusions:

  • High clinical suspicion is essential due to non-specific symptoms.
  • Diagnosis and management are severity-dependent.
  • Preventive strategies are being explored pre- and post-operatively.