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Infections Following Gender-Affirming Vaginoplasty: A Single-Center Experience

Radhika Sheth1, Apoorva Bhaskara2, Haley Brown3

  • 1Division of Infectious Disease, Oregon Health & Science University, Portland, Oregon, USA.

Open Forum Infectious Diseases
|October 16, 2024
PubMed

Insights

Post-gender-affirming vaginoplasty, urinary tract and surgical site infections are common. There is a notable need for improved human immunodeficiency virus screening and pre-exposure prophylaxis prescription.

Area of Science:

  • Urology
  • Infectious Diseases
  • Transgender Health

Background:

  • Gender-affirming surgeries are increasingly common.
  • Understanding post-operative infection rates is crucial for patient outcomes.

Purpose of the Study:

  • To determine the epidemiology and incidence of infections after gender-affirming vaginoplasty.
  • To assess human immunodeficiency virus (HIV) screening and pre-exposure prophylaxis (PrEP) practices in this population.

Main Methods:

  • Retrospective analysis of patient data following vaginoplasty.
  • Tracking of infection types, incidence rates, and diagnostic codes.
  • Review of HIV screening and PrEP prescription records.

Main Results:

  • Urinary tract infections (UTIs) occurred in 17.5% of patients.
  • Surgical site infections (SSIs) occurred in 5.5% of patients.
  • Significant underutilization of HIV screening and PrEP was observed.

Conclusions:

  • UTIs and SSIs represent the most frequent complications post-vaginoplasty.
  • There is a critical need to enhance HIV prevention strategies, including screening and PrEP, for individuals undergoing gender-affirming surgery.
Keywords:
HIVUTIgender-affirming caresurgical infectionstransgender

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