Uncontrolled Donation Potential After Circulatory Death in Slovenia Could Lead to More Organ Donations: Extrapolation

Domen Kulovec1, Luka Petravić2, Rok Miklič

  • 1General Hospital of Novo mesto, Novo mesto, Slovenia.

Insights

Implementing uncontrolled donation after circulatory death in Slovenia could significantly increase organ availability. This approach, applied to out-of-hospital cardiac arrest patients, shows potential for saving lives.

Area of Science:

  • Cardiology
  • Transplantation Medicine
  • Public Health

Background:

  • Out-of-hospital cardiac arrest (OHCA) presents a significant public health challenge in developed nations.
  • Organ donation after circulatory death (DCD) offers a vital source of organs for transplantation.
  • A substantial number of patients die while awaiting organ transplants globally.

Purpose of the Study:

  • To evaluate the feasibility of uncontrolled donation after circulatory death (uDCD) for OHCA patients in Slovenia.
  • To estimate the potential number of uDCD donors among OHCA cases in Slovenia.

Main Methods:

  • A non-interventional study utilizing the Slovenian OHCA registry data from September to November 2022.
  • Patient selection based on established uDCD donor criteria.
  • Extrapolation of findings to estimate the annual donor potential.

Main Results:

  • The study identified 19 potential donors from 294 OHCA patient records based on uDCD criteria.
  • No actual organ donors were found within the selected cohort.
  • Extrapolation suggests a potential of 111 uDCD donors annually in Slovenia (52.4 per million population).

Conclusions:

  • An uncontrolled donation after circulatory death program in Slovenia holds significant potential to increase organ availability.
  • The findings provide a foundation for further research into uDCD in Slovenia and comparable healthcare systems.
  • Despite limitations of sample size and study duration, the results indicate a positive impact on patients awaiting transplants.