Related Experiment Video
Updated: Jun 10, 2025

10:52
Preparation of Mouse Pituitary Immunogen for the Induction of Experimental Autoimmune Hypophysitis
Published on: December 17, 2010
14.6K
Isolated IgG4-related Infundibulo-hypophysitis
Margaret E Allen1, Ryan T Beck2, Nathan T Zwagerman3
1Medical College of Wisconsin, Milwaukee, WI 53226 USA.
JCEM Case Reports
|October 17, 2024
Summary
This case study highlights IgG4-related hypophysitis, a rare cause of sellar masses. Early diagnosis and steroid treatment are key for managing this condition, even without systemic IgG4 disease.
Area of Science:
- Endocrinology
- Neurology
- Pathology
Background:
- A 72-year-old man presented with symptoms of hypopituitarism, including weakness, poor appetite, and depressed mood.
- Imaging revealed a suprasellar mass affecting the hypothalamus and pituitary stalk.
Related Concept Videos
Transcytosis of IgG
2.7K
Transcytosis is the process in which molecules are internalized by endocytosis, transported across the cell, and released through exocytosis from the opposite end of the cell. Molecules such as insulin, immunoglobulins, and certain nutrients are transferred through the recycling endosomes by recycling and transcytosis.
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
2.7K
Irritable Bowel Syndrome I: Introduction
254
Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
254
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
146
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
146

