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Updated: Jun 10, 2025

Methods to Increase the Sensitivity of High Resolution Melting Single Nucleotide Polymorphism Genotyping in Malaria
Published on: November 10, 2015
Progress in malaria genomic surveillance using long-read sequencing
Julia Zerebinski1, David F Plaza1
1Karolinska Institutet, Division of Infectious Diseases, Department of Medicine Solna and Center for Molecular Medicine, Stockholm, Sweden; Karolinska University Hospital, Department of Infectious Diseases, Stockholm, Sweden.
Abstract:
Recent studies by Girgis et al. and de Cesare et al. promise to advance malaria genomic surveillance using inexpensive and portable long-read amplicon-sequencing technologies. These technologies allow rapid characterization of drug-resistance markers, antigenic diversity, and diagnostic target loci from dried blood spots, providing new tools for surveillance in endemic regions and informing interventions to combat malaria more effectively.

